The International Virus Bioinformatics Meeting 2022 (ViBioM 2022) took place online, 23–25 March 2022. The meeting was jointly organized by the European Virus Bioinformatics Center (EVBC), the Institute of Agrochemistry and Food Technology (IATA-CSIC), and the University of Valencia.
ViBioM 2022 was planned to take place in Valencia, Spain. As the number of Omicron cases in Europe has been rapidly increasing in January 2022, we decided to again switch to an online format to avoid creating a transmission hotspot for SARS-CoV-2 and to make the conference planning less complicated (in terms of safety regulations and travel restrictions).
ViBioM 2022 offered a great possibility to exchange the latest research results and experiences with an extensive network of leading experts in virology and bioinformatics and engage in inspiring discussions. Our aim was to encourage and assist scientific exchange in both areas and initiate scientific cooperation. The meeting focused on bioinformatics approaches in virology and welcomed any contributions dealing with the recent advancements and current understanding of computational technology of virology.
We had an incredibly high amount of registered participants. Even during the ongoing conference, there were registrations up to the last day. There was a lot of fluctuation among the 380 registered participants and not everyone attended all talks. However, we had a solid base of between 100–150 participants during each of the talks. Of all registered participants, ~19% are EVBC members, so ViBioM is attracting scientists far beyond the EVBC community.
As in 2020, the participants made it possible to create a highly interactive scientific environment even without physical face-to-face interactions. Breakout rooms of the speakers for continued discussion during the coffee breaks have been extensively used.
In total, the meeting featured eight invited and 18 contributed talks in eight sessions on three days, as well as 52 posters which were presented during three virtual poster sessions.
Invited Speakers
Awardees
Best ECR Talk Award: Spyros Lytras
Best Poster Awards: Luca Nishimura, Celia Pas, Gabriel Lenconi Lovate
Special Issues and Conference Report
Simultaneously to the meeting, we have published a special issue on Virus Bioinformatics in Viruses, including a conference report summing up the meeting.
Program Schedule
You can find the abstracts here.
Wednesday, 23rd March: Satellite Meeting on SARS-CoV-2
9:45 | Welcome |
MORNING SESSION Chair: Martin Hölzer |
|
10:00–10:30 | The changing landscape of SARS-CoV-2 genetic diversity Francois Balloux, University College London, UCL Genetics Institute, Computational Systems Biology |
10:30–10:50 | covSonar: Efficient and rapid genome profiling of SARS-CoV-2 sequences Alice Wittig, Hasso Plattner Institute, Robert Koch Institute, Data Analytics and Computational Statistics, Bioinformatics, Berlin, Germany |
10:50–11:10 | COFFEE BREAK |
11:10–11:30 | The emergence of SARS-CoV-2 variants of concern is driven by acceleration of the substitution rate Sebastian Duchene, University of Melbourne, Australia |
11:30–11:50 | VOCAL: An early warning system to detect concerning new SARS-CoV-2 variants from sequencing data Kunaphas Kongkitimano, Robert Koch Institute, MF1 – Bioinformatics, Berlin, Germany |
11:50–13:00 | LUNCH BREAK |
13:00–14:30 | Poster Session on SARS-CoV-2 |
AFTERNOON SESSION Chair: Fernando Gonzales-Candelas |
|
14:30–15:00 | SARS-CoV-2 genomic epidemiology: Bayesian phylodynamic reconstruction and characterization of antigenic evolution Philippe Lemey, Evolutionary and Computational Virology, KU Leuven, Belgium |
15:00–15:20 | ImpuSARS: A new tool for whole-genome imputation of SARS-CoV-2 Francisco Ortuño, Fundación Progreso y Salud, Área de Bioinformática Clínica, Sevilla, Spain |
15:20–15:40 | COFFEE BREAK |
15:40–16:00 | National-scale surveillance of emerging SARS-CoV-2 variants in wastewater Fabian Amman, CeMM – Forschungszentrum für Molekulare Medizin, Vienna, Austria |
16:00–16:20 | The power of SARS-CoV-2 genotyping and SNP-based clustering for contextual outbreak assessment Denis Beslic, Robert Koch Institute, MF1, Berlin, Germany |
16:20–17:00 | FINAL COFFEE |
19:00 | 5 Years EVBC Birthday Celebration |
Thursday, 24th March
9:00 | Welcome |
Session 1: Viral emergence and surveillance Chair: Magda Bletsa |
|
09:30–10:00 | Real-time to Real-life: Phylogenetics, Pandemics, and What Comes Next Emma Hodcroft, Institute of Social and Preventive Medicine, University of Bern, Switzerland |
10:00– 10:30 | Can genomics help prevent viral emergence? Daniel Streicker, Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, United Kingdom |
10:30–10:50 | Genomic Surveillance of the Rift Valley fever: from Sequencing to Lineage assignment John Juma, International Livestock Research Institute/University of Western Cape, Animal and Human Healt, Nairobi, Kenya |
10:50–11:10 | COFFEE BREAK |
Session 2: Virus-host interactions Chair: Kevin Lamkiewicz |
|
11:10–11:40 | Diverse anti-interferon strategies by members of the genus phlebovirus Friedemann Weber, Institute for Virology, Gießen, Germany |
11:40–12:00 | Staying below the radar and exploiting the host – A toolbox for studying RNA virus – host factor interactions Andreas Gruber, University of Konstanz, Department of Biology, Konstanz, Germany |
12:00-12:20 | Multi-omics reveals principles of gene regulation and pervasive non-productive transcription in the human cytomegalovirus genome Christopher Jürges, University of Würzburg, Germany |
12:20–13:30 | LUNCH BREAK |
13:30–15:30 | Poster Session A |
Session 3: Viral Sequence analysis Chair: Daniel Todt |
|
15:30–16:00 | Origins and implications of the quasispecies concept Esteban Domingo, Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), Madrid, Spain |
16:00–16:20 | A guidance to store your virus sequence and knowledge Muriel Ritsch, Friedrich Schiller University Jena, Jena, Germany |
16:20–16:40 | Exploring the dinucleotide composition of the Flaviviridae with DinuQ Spyros Lytras, MRC – University of Glasgow Centre for Virus Research, Glasgow, UK |
16:40–17:00 | Genotype-based classification of IAV to unravel reassortment candidates Alexander Henoch, Friedrich Schiller University Jena, Faculty of Mathematics and Computer Science, Jena, Germany |
17:00–17:30 | FINAL COFFEE |
19:00 | Ask me Anything wih the keynote speakers |
Friday, 25th March
9:15 | Welcome |
Session 4: Virus identification and annotation Chair: Alba Pérez-Cataluña |
|
09:30–09:50 | VirSorter2: a multi-classifier, expert-guided approach to detect diverse DNA and RNA viruses Jiarong Guo, Ohio State University, Microbiology, United States |
09:50–10:10 | Evaluation of gene-calling programs for viral genome annotation Enrique Gonzalez-Tortuero, University of Salford, United Kingdom |
10:10–10:30 | COFFEE BREAK |
10:30–11:30 | EVBC Meeting: Updates and future perspectives of the EVBC |
11:30–12:45 | Poster Session B |
12:45–14:00 | LUNCH BREAK |
Session 5: Phages Chair: Noriko Cassman |
|
14:00–14:30 | Phages in the human gut: a taxonomist’s perspective Evelien Adriaenssens, Quadram Institute Bioscience, Norwich Research Park, Norwich, UK |
14:30–14:50 | Dual identification of novel phage receptor-binding proteins based on protein domains and machine learning Dimitri Boeckaerts, Ghent University, Laboratory of Applied Biotechnology, Ghent, Belgium |
14:50–15:10 | Predicting viral capsid architectures from metagenomes Antoni Luque, San Diego State University, Viral Information Institute, San Diego, United States |
15:10–15:30 | COFFEE BREAK |
Session 6: Viral diversity Chair: Manja Marz |
|
15:30–16:00 | Ocean viruses: Patterns, processes, and paradigms on a planetary scale Matthew Sullivan, Ohio State University, United States |
16:00–16:20 | Community typing as a way to explore virome compositional changes in IBD patients Daan Jansen, KU Leuven, Department of Immunology, Microbiology and Transplantation, Leuven, Belgium |
16:20–16:40 | vAMPirus: An automated virus amplicon sequence analysis program to support investigations of viral community ecology Alex Veglia, Rice University, Department of BioSciences, Houston, United States of America |
16:40–16:50 | COFFEE BREAK |
16:50–17:30 | Discussion / Best Poster and Talk / Closing Ceremony |
19:00 | ViBioM Game Night |
Poster Sessions
Poster Session on SARS-CoV-2: Wednesday, 23rd March
S01 | Population genetics and evolution of SARS-CoV-2 around the Delta variant emergence Miguel Álvarez Herrera | Institute for Integrative Systems Biology, Valencia, Spain |
S02 | Near-full compression of SARS-CoV-2 peptidome Li Chuin Chong | TWINCORE Gmbh, Hannover, Germany |
S03 | Comparison of Results from Three Different Algorithms of In Silico Interaction Between Onosmone and Sars-CoV-2 Main Protease Tarik Corbo | University of Sarajevo, Institute for Genetic Engineering and Biotechnology, Sarajevo, Bosnia and Herzegovina |
S04 | Impact of SARS-CoV-2 lineages on the survival of hospitalized patients Carlos Sánchez and Carlos Loucera | Fundacion Progreso y Salud, Sevilla, Spain |
S05 | The Andalusian circuit for SARS-CoV-2 whole genome sequencing Javier Pérez-Florid | Fundacion Progreso y Salud, Sevilla, Spain |
S06 | SARS-CoV-2 variants preferentially emerge at intrinsically disordered protein sites helping immune evasion Federica Quaglia | University of Padua, Padova, Italy |
S07 | Relevant mutations in SARS-CoV-2 with strong genetic association to phenotypes of interest Paula Ruiz-Rodriguez | I2SysBio, Paterna, Spain |
S08 | Viral Instant Mutation Viewer (VIMVer): a tool to speed up the identification and analysis of new SARS-CoV2 emerging variant Vincent Wilde | UMR 7257 (AFMB), Marseille, France |
S09 | Application of next-generation sequencing in selected Latvian SARS-CoV-2 outbreak investigations of particular interest Nikita Zrelovs | Latvian Biomedical Research and Study Centre, Riga, Latvia |
S10 | Assessment of CDC’s COVID Data Tracker Nowcast Model Accuracy and Reliability Philip Shirk | Centers for Disease Control, Atlanta, USA |
Poster Session A: Thursday, 24th March
A01 | DRUMMER – Rapid detection of RNA modifications through comparative nanopore sequencing Jonathan Abebe | New York University, New York, United States |
A02 | Finding genetic markers of zoonotic transmission of Influenza A virus using phylogenetic inference on large datasets Klara Marie Andersen | Technical University of Denmark, Kgs. Lyngby, Denmark |
A03 | Evolutionary history of peste des petits ruminants virus Arnaud Bataille | CIRAD, Montpellier, France |
A04 | Molecular epidemiology of the hematophagous bat genetic variant in Colombia and its relationship whit other countries of Latin-America Maria Fernanda Carreño | Instituto Nacional de Salud, Bogota, Colombia |
A05 | Using phylogenetics and RNA structure predictions tools to generate hypotheses on the mechanisms of avian influenza virus evolution towards highly pathogenic forms Gabriel Dupré | ENVT / INRAE, Toulouse, France |
A06 | Error correction and local haplotype reconstruction for NGS data Lara Fuhrmann | ETH Zurich, Basel, Switzerland |
A07 | Intra-host analysis of hepaciviral glycoprotein evolution reveals signatures associated with viral persistence and clearance André Gömer | Ruhr-University Bochum, Bochum, Germany |
A08 | Beyond the genome: The diverse and dynamic post-translational modification landscape of betacoronaviruses as a driver of rapid evolutionary adaptation Jessica Gonzalez | Florida International University, Miami, USA |
A09 | Is Rigvir a potential oncolytic virotherapy agent? Genome comparisons and cytolytic properties of Rigvir and other echovirus 7 isolates Eero Hietanen | University of Turku, Turku, Finland |
A11 | A comprehensive overview of RNA-Protein interaction prediction methods Sarah Krautwurst | Friedrich Schiller University Jena, Jena, Germany |
A12 | RNA modification detection from raw nanopore signals Sebastian Krautwurst | Friedrich Schiller University Jena, Jena, Germany |
A13 | Say Hello to the Lamkiewicz-Lab: RNA-Protein-Interactions and more! Kevin Lamkiewicz | Friedrich Schiller University Jena, Jena, Germany |
A14 | Reproducible RNA-RNA interaction probing for RNA proximity ligation data with RNAswarm Gabriel Lencioni Lovate | Friedrich Schiller University Jena, Jena, Germany |
A15 | COAST: A bioinformatic tool to identify the closest proteomes Diogo Macedo | Universiade do Minho, Braga, Portugal |
A16 | HIV transmission network analysis Daiana Mir | Universidad de la República (UdelaR), Salto, Uruguay |
A17 | Molecular epidemiology of Rotavirus in Tehran, Iran; rare and unusual G9P[8] and G6P[14] types among children with acute gastroenteritis Seyed Reza Mohebbi | Shahid Beheshti University of Medical Sciences, Tehran, Iran |
A19 | Genomic plasticity: Role of Hepatitis E virus genome insertions in viral fitness and resistance Maximilian Klaus Nocke | Ruhr University Bochum, Bochum, Germany |
A20 | Molecular Epidemiology of measles in Colombia: outbreak description 2017-2020 Carolina Peña Guzman | Instituto Nacional de Salud, Bogota, Colombia |
A21 | GrandR: leveraging the power of RNA metabolic labeling to record transcriptional activity in single cells Lygeri Sakellardi | University of Würzburg, Würzburg, Germany |
A22 | Identification and characterization of enzymes linked with evolution and stable genome size increase of large (+) RNA viruses. Bhawna Sama | Aix-Marseille Université, Marseille, France |
A23 | Detection of intra-subtype recombination events within transmission clusters Anahi Sánchez | Universidad Autónoma de la Ciudad de México, Ciudad de México, México |
A24 | Bioinformatic techniques to identify minor variations in influenza virus sequences generated using NGS technology Sandra Seby | Centers for Disease Control, Atlanta, USA |
A25 | Residue interaction network analysis of A(H1N1)pdm09 hemagglutinin evolution within antibody combining site Sb from 2009 to present Nicholas A Kovacs | Centers for Disease Control, Atlanta, USA |
A26 | RNASIV: Database of predicted viral mRNA structures Franziska Totzeck | Technical University Munich, Munich, Germany |
A27 | Real-time and remote MCMC trace inspection with Beastiary Wytamma Wirth | The University of Melbourne, Victoria, Australia |
A28 | Method for Influenza Assay Primer Mismatch Detection Norman Hassell | Centers for Disease Control, Atlanta, USA |
Poster Session B: Friday, 25th March
B01 | Viral diversity and co-evolution with Fungal and Oomycete pathogens Alexander Allman | University of Greenwich, Gillingham, United Kingdom |
B02 | Host prediction from shotgun viromic data vs. 16S rRNA gene amplicon sequencing for deciphering marine phage-host interactions Felana Harilanto Andrianjakarivony | M.I.O. Institut Méditerranéen d’Océanologie Campus de Luminy – OCEANOMED, Marseille, France |
B03 | Expanding our knowledge on the diversity of invertebrate RNA viruses in the largest taxon sampling so far Anamarija Butkovic | CSIC I2SYSBIO, Valencia, Spain |
B04 | LABRADOR – a workflow for virus detection in HTS data Izabela Fabianska | IDT Biologika GmbH, Dessau-Roßlau, Germany |
B05 | Exploring the epidermal virome of carcharhinid sharks Ryan Hesse | San Diego State University, San Diego, United States |
B06 | The virome in IBD patients undergoing biological therapy Daan Jansen | KU Leuven, Leuven, Belgium |
B07 | The virome of Freesia hyb. showing leaf necrosis syndrome Laura Miozzi | Institute for Sustainable Plant Protection, Torino, Italy |
B08 | Virome analyses of the ancient individuals who lived in the Japanese archipelago 3,000 years ago Luca Nishimura | National Institute of Genetics, Mishima, Japan |
B09 | Transposable Prophages in Leptospira: An Ancient, Now Diverse, Group Predominant in Causative Agents of Weil’s Disease Eric Olo Ndela | Université Clermont Auvergne, Clermont-Ferrand, France |
B10 | Genomic determinants of viral host diversity Marina Parr | Technical University of Munich, Munich, Germany |
B11 | A blueprint of tail fiber modularity and its relationship with host specificity for STEC serovars Célia Pas | Ghent University, Ghent, Germany |
B12 | Introducing the National Research Data Infrastructure for the Research of Microbiota (NFDI4Microbiota) Kristin Sauerland | Helmholtz Centre for Infection Research GmbH, Braunschweig, Germany |
B13 | Domain architecture shows extensive mosaicism of phage receptor binding proteins Bogna Smug | Jagiellonian University in Krakow, Kraków, Poland |
B14 | Comprehensive discovery of CRISPR targeted sequences from the human gut metagenome Ryota Sugimoto | National Institute of Genetics, Mishima Shizuoka, Japan |
B15 | Characterization of gut phages in HIV-infected patients Pablo Villoslada-Blanco | Center for Biomedical Research of La Rioja (CIBIR) / Universidad de La Rioja, Logroño, Spain |
B16 | Deep learning models for the Identification of novel viruses Yasas Wijesekara | University of Greifswald, Greifswald, Germany |